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Ira Tabas, MD, PhD
Richard J. Stock Professor and Vice-Chair of Research
Department of Medicine
Professor of Pathology & Cell Biology (in Physiology and Cellular Biophysics)
Columbia University Medical Center

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Brief Biography of Dr. Tabas:

Dr. Tabas is the Richard J. Stock Professor of Medicine, Cell Biology, and Physiology at Columbia University Medical Center (CUMC). He received his M.D. and Ph.D. degrees from Washington University in St. Louis and completed his Internal Medicine and Endocrinology/Metabolism training at CUMC, with board certification in both disciplines. His research focuses on cardiometabolic disease, with a long history of work in the area of molecular-cellular mechanisms of advanced atherosclerosis. His research has elucidated roles of macrophage endoplasmic reticulum (ER) stress, apoptosis, defective efferocytosis, and defective inflammation resolution in advanced plaque progression. Over the last ten years, Dr. Tabas' laboratory has expanded its interests into an area that is a major driving force behind atherosclerosis, namely, obesity-associated type 2 diabetes (T2D). In particular, the laboratory has discovered a new calcium-ER stress signaling pathway in hepatocytes that contributes to the metabolic disturbances of obesity and diabetes. In both the atherosclerosis and metabolism areas, there is strong emphasis on therapeutic translation. In this context, Dr. Tabas is co-founder of Tabomedex Biosciences, LLC, which is developing a new drug strategy for T2D. He has lectured worldwide and published over 200 original research articles and reviews. These papers have been published in Cell, Nature, Science, Nature Cell Biology, Nature Reviews Immunology, Cell Metabolism, Journal of Clinical Investigation, Proceedings of the National Academy of Sciences, and other top journals. Dr. Tabas also serves on the Board of Reviewing Editors for the journal Science. He was elected to both the Society for Clinical Investigation and the Association of American Physicians. Dr. Tabas' other honors include the American Heart Association Established Investigator Award, the Columbia University Doctor Harold and Golden Lamport Research Award, the American Heart Association/ATVB Council Special Recognition Award, the 2011 Alumni Achievement Award from Washington University School of Medicine, the 2014 Society of Leukocyte Biology Bonazinga award, which is the society's highest honor for excellence in leukocyte biology research, the 2015 Harrington Discovery Institute Innovator-Scholar Award for his work in diabetes, and the 2016 American Heart Association Russell Ross Lectureship Award in Vascular Biology..

 

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